| Thyroid
Symptoms
of thyroid imbalance are many. Some of the more common
symptoms are weight gain, fatigue, hair, nail and skin
problems, depression, cold hands and feet, increased
cholesterol, bad memory, anxiety, constipation, lack
of concentration, changes in menstruation, goiter and
difficulty swallowing.
Many
people who are currently on thyroid hormone replacement
(Synthroid, Levoxyl, Armour, Cytomel, etc.) still complain
of thyroid symptoms even though their doctors assure
them that their TSH levels are back
within normal ranges and everything is “normal”.
Patients know better. In fact, almost half of patients
on thyroid hormone therapy still complain of the same
symptoms that they had before starting on hormone replacement.
In these situations BRT has shown great promise in improving
these remaining symptoms.
Perhaps
even more disconcerting is when a person has all the
classic thyroid symptoms but their doctor says that
their blood tests are normal. BRT analysis can tell
if there is indeed a problem with the thyroid, a problem
with the receptor sites for the thyroid hormones at
the target cells or whether the thyroid function is
being affected by another organ’s hormones.
Chronic
stress will cause high levels of the adrenal hormone
cortisol to suppress the pituitary gland’s production
of TSH causing subjective symptoms such as reduced or
absent sex drive, abnormal thirst, lack of menstruation
and weight gain around the hips and waist.
Elevated
cortisol also has a suppressive effect on an enzyme
called 5’deiodinase, which converts the relatively
inactive thyroid hormone T4 into the more active T3.
Elevated cortisol will decrease active T3 levels and
reduce the gene expression by the thyroid
hormones, again causing the typical hypothyroid symptoms.
As
with all endocrine problems, BRT checks the hormonal
feedback loops to the brain for communication problems.
The hypothalamus region of the brain
produces a hormone called thyroid releasing hormone
(TRH), which travels via the blood to the pituitary
gland at the base of the brain. The TRH stimulates
the pituitary to release thyroid stimulating hormone
(TSH), which in turn travels to the thyroid gland and
stimulates it to produce the thyroid hormones T3,
T4, and calcitonin.
These hormones go to virtually all the cells of the
body, carrying an instruction to the nucleus of the
cells to produce various proteins, enzymes and other
cellular products needed by the body (gene expression).
The circulating thyroid hormone concentrations in the
blood are constantly monitored by the hypothalamus.
If they become too high the hypothalamus decreases its
production of TRH. If it becomes too low it increases
TRH. This mechanism works very similar to a thermostat
used to control temperature in our houses.
Thyroid
function can also be negatively influenced by a malfunctioning
immune system. The immune system can sometimes become
confused and produce antibodies to a pathogen or toxin
which then inappropriately attaches to the receptor
sites of the thyroid stimulating hormones on the thyroid
gland. These antibodies then either over or under stimulate
the thyroid, causing diseases like Grave’s disease
or Hashimoto’s thyroiditis. BRT has also shown promise with these autoimmune conditions.
Disclaimer:
All material provided in this website is provided for
educational purposes only. Consult your physician regarding
the applicability of any information provided in this
website to your symptoms or medical condition.
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